Normally, her shrine would be small, located only on the outskirts of the village, and built with ordinary stones, because the great divine mother does not want to enjoy any other comforts in her temple. Even so, during the Aadi month, her ardent devotees would adorn her with silk saris and offer non vegetarian food as a token of their deep respect for her. Ma Poleramma is revered for curing diseases such as smallpox, chicken pox, and measles, as well as curing dreaded virus diseases and a variety of other ailments.

She is also thought to be the sister of Muthu Mariamman, a form of Shakti worshipped by Tamil Nadu devotees. Poleramma's devotees worship her by chanting her 100 names and performing puja and abhishekham to the holy goddess, especially on festival days and Tuesdays and Fridays. Parvati Devi, Lord Shiva's consort who is also known as Durga, Shakti, and Chamundi, has taken various avatars throughout India. Among her numerous avatars, Ma Poleramma is regarded as the most noble.

People worship Ma Poleramma to rid themselves of the negative effects of planetary positions, as well as to prevent bad thoughts from entering their minds, and her male devotees regard all females as incarnations of Ma Shakti Devi.